Gynandroblastoma in pregnancy: case report and review of literature.

Abstract

Gynandroblastoma is an extremely rare tumor, composed of sex cord and stromal cells of both ovarian (granulosa-theca) and testicular (Sertoli-Leydig) types. We believe that its occurrence during pregnancy has not been previously reported. The patient was a 32-year-old woman who during her pregnancy was noted to have a progressively enlarging, unilocular left ovarian cyst. Beginning at 18 weeks gestation, the fetus required multiple platelet transfusions for severe alloimmune thrombocytopenia. A viable baby girl was delivered by cesarean section at 39 weeks gestation. At that time, an ovarian cystectomy also was performed. When the histology of the tissue subsequently became known, a left salpingo-oophorectomy was performed for gynandroblastoma. One year later, at the time of laparoscopic sterilization, the examination of the pelvis was normal.

• Authors: T Kalir, F Friedman Jr
• Journal: The Mount Sinai journal of medicine, New York (Mt Sinai J Med) Vol. 65 Issue 4 Pg. 292-5 (Sep 1998) ISSN: 0027-2507 [Print] United States
• PMID: 9757751 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adult
• Female
• Humans
• Neoplasms, Gonadal Tissue (complications, pathology, surgery)
• Ovarian Cysts (complications, pathology, surgery)
• Ovarian Neoplasms (complications, pathology, surgery)
• Pregnancy
• Pregnancy Complications, Neoplastic (pathology, surgery)
• Pregnancy Trimester, Second