Abstract | PURPOSE: SUBJECTS AND METHODS: Published or unpublished articles were sought using MEDLINE, reference review, and correspondence with original authors, catheter manufacturers, and experts. Trials using silver-coated urinary catheters in the treatment group and uncoated urinary catheters in the control group were included. Bacteriuria, as evaluated by urine culture, was the outcome variable used to indicate urinary tract infection. Summary odds ratios (OR) and 95% confidence intervals (CI) were calculated using Mantel-Haenszel methods with a fixed-effects model. RESULTS: Of 117 reports retrieved, eight trials with a total of 2,355 patients satisfied inclusion criteria. The summary OR for urinary tract infection was 0.59 (95% CI, 0.42 to 0.84) indicating a significant benefit in the patients receiving silver-coated catheters. A test of heterogeneity, however, indicated that the odds ratios varied significantly among studies. Silver alloy catheters (OR = 0.24; 95% CI, 0.11 to 0.52) were significantly more protective against bacteriuria than silver oxide catheters (OR = 0.79; 95% CI, 0.56 to 1.10). CONCLUSIONS:
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Authors | S Saint, J G Elmore, S D Sullivan, S S Emerson, T D Koepsell |
Journal | The American journal of medicine
(Am J Med)
Vol. 105
Issue 3
Pg. 236-41
(Sep 1998)
ISSN: 0002-9343 [Print] United States |
PMID | 9753027
(Publication Type: Journal Article, Meta-Analysis)
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Chemical References |
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Topics |
- Alloys
- Humans
- Odds Ratio
- Silver
- Urinary Catheterization
(instrumentation)
- Urinary Tract Infections
(etiology, prevention & control)
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