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Pupil-sparing third nerve palsy associated with sildenafil citrate (Viagra).

AbstractPURPOSE: To report unilateral pupil-sparing third nerve palsy after use of sildenafil citrate (Viagra). METHOD: Case report. RESULTS: A 56-year-old man with a history of tobacco abuse was treated for erectile dysfunction. Viagra, 50 mg, was taken once without adverse effect. Three weeks later, the patient took a second dose of Viagra (50 mg); 36 hours later he experienced a complete pupil-sparing third nerve palsy. Erythrocyte sedimentation rate, blood glucose level, magnetic resonance imaging, and magnetic resonance angiography were normal. CONCLUSION: In a patient with microvascular disease, use of sildenafil may be associated with pupil-sparing third nerve palsy.
AuthorsS P Donahue, R J Taylor (Affiliation: Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.)
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 126 Issue 3 Pg. 476-7 (Sep 1998) ISSN: 0002-9394 UNITED STATES
PMID9744392 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Blood Glucose
  • Enzyme Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • sildenafil
Topics
  • Blood Glucose (analysis)
  • Blood Sedimentation
  • Enzyme Inhibitors (adverse effects)
  • Humans
  • Iris (innervation)
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Oculomotor Nerve Diseases (chemically induced)
  • Piperazines (adverse effects)
  • Pupil
  • Purines
  • Sulfones