Normal intrasylvian anatomical asymmetry in children with developmental language disorder.

Abstract

Symmetry of posterior intrasylvian cortices (e.g., planum temporale, planum parietale) has been suggested to represent a risk factor for developmental disorders of language and reading. Using high-resolution magnetic resonance morphometry, we studied 21 right-handed children with developmental language disorder of the phonologic-syntactic type, and found normal left-right asymmetry of the planum temporale and planum parietale when compared with 21 matched controls. The planum temporale was bilaterally smaller in the affected children, a finding accounted for by their approximately 7% smaller forebrain size. Our data do not support a role of gross visible unilateral or bilateral abnormalities of posterior intrasylvian ontogenesis in this disorder.

• Authors: S Preis, L Jäncke, P Schittler, Y Huang, H Steinmetz
• Journal: Neuropsychologia (Neuropsychologia) Vol. 36 Issue 9 Pg. 849-55 (Sep 1998) ISSN: 0028-3932 [Print] England
• PMID: 9740358 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Analysis of Variance
• Anthropometry
• Case-Control Studies
• Child
• Child, Preschool
• Female
• Functional Laterality
• Humans
• Language Development Disorders (classification, pathology)
• Magnetic Resonance Imaging
• Male
• Parietal Lobe (pathology)
• Prosencephalon (pathology)
• Regression Analysis
• Temporal Lobe (pathology)