Abstract |
A number of N-[(4-aryl)- or (4-methyl)-l-piperazinyl)alkyl]imides of 3-aryl or 3,3-pentamethylenesuccinic acid were synthesized and tested for anticonvulsant activity in the maximum electroshock seizure (MES) and pentylenetetrazole seizure threshold (scMet) tests. Structures of the novel compounds were confirmed by elemental and spectral analyses.
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Authors | J Obniska, K Kulig, A Zejc |
Journal | Acta poloniae pharmaceutica
(Acta Pol Pharm)
Vol. 55
Issue 3
Pg. 223-31
( 1998)
ISSN: 0001-6837 [Print] Poland |
PMID | 9735703
(Publication Type: Journal Article)
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Chemical References |
- Anticonvulsants
- Piperazines
- Succinates
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Topics |
- Animals
- Anticonvulsants
(chemical synthesis, pharmacology)
- Electroshock
- Mice
- Piperazines
(chemical synthesis, pharmacology)
- Seizures
(prevention & control)
- Structure-Activity Relationship
- Succinates
(chemical synthesis, pharmacology)
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