Bacteriocin (klebocin) sensitivity typing of klebsiella.

Abstract

High-titer preparations of Klebsiella bacteriocins (klebocins) were obtained by using mitomycin to induce standard strains of Klebsiella. Of 296 clinical isolates of Klebsiella, 67% could be typed on the basis of their sensitivity to klebocins. The method proposed in this paper affords a standard basis for the further development of klebocin typing as a suitable procedure for hospital laboratories concerned with epidemiological investigations of hospital-associated infections. Evidence is also provided to show that high-titered klebocin typing can be used in conjunction with biochemical typing to provide a sensitive epidemiological marker for Klebsiella.

• Authors: C L Buffenmyer, R R Rycheck, R B Yee
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 4 Issue 3 Pg. 239-44 (Sep 1976) ISSN: 0095-1137 [Print] United States
• PMID: 972191 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Bacteriocins
• Mitomycins

Topics

• Adult
• Bacteriocins (biosynthesis, pharmacology)
• Drug Resistance, Microbial
• Female
• Humans
• Infant, Newborn
• Infant, Newborn, Diseases (microbiology)
• Klebsiella (classification, drug effects, metabolism)
• Klebsiella Infections (microbiology)
• Mitomycins (pharmacology)
• Pregnancy
• Pregnancy Complications, Infectious (microbiology)
• Ultraviolet Rays