The effects of various metallic
ions using various metallic powders on the relative growth ratio of fibroblasts L929 and osteoblasts MC3T3-E1 cells were carried out. Ti, Zr, Sn, Nb and Ta had evidently no effect on the relative growth ratios of cells. Otherwise, Al and V
ions exhibit cytotoxicity from a concentration of > or = 0.2 ppm. This Al effect on cells tend to be stronger in medium containing small quantity of V
ions (< or = 0.03 ppm). The new Ti-15%Zr-4%Nb-4%Ta-0.2%Pd
alloy exhibited a higher corrosion resistance in physiological
saline solution. The addition of 0.02%O and 0.05%N to
Ti-Zr alloy improved the mechanical properties at room temperature and corrosion
fatigue strength. The relative growth ratios for the new Ti
alloy plate and the
alloy block extraction were unity. Further, the relative growth ratios were almost unity for the new Ti
alloy against
apatite ceramic pins up to 10(5) wear cycles in Eagle's MEM
solution. However, there was a sharp decrease for Ti-6%Al-4%V ELI
alloy from 3 x 10(4) wear cycles as V ion was released during wear into the wear test
solution since the pH of the Eagle's MEM increases with increasing wear cycles.