HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Implantable central venous access devices in children with metabolic disease.

Abstract
We have inserted 20 totally implantable central venous devices in 17 patients with severe metabolic disease over a 43-month span. Patient ages ranged from 2 months to 17 years (mean, 4.2 years). The underlying pathology was Gaucher's disease in six patients, vitamin D-dependent rickets type II in five, propionic acidemia in two, and methylmalonic acidemia, 3-hydroxyl-3-methylglutaryl coenzyme A (CoA) lyase deficiency, fructose 1,6 diphosphatase deficiency, and urea cycle disorder in one child each. There were seven complications (six due to catheter-related infection and one due to occlusion of the system) during a total of 7,278 patient-catheter days. The infection rate was 0.8 per 1,000 days. Six catheters were removed due to complications and two due to completion of treatment. There were no operative complications or deaths. Our experience demonstrates that a totally implantable device may be useful in children with metabolic disease who need long-term venous access. Attention should be given to minimize the infection rate to reduce the rate of catheter removal.
AuthorsA Al-Bassam, A Al-Rabeeah, K Fouda, A Al-Ashwal, P T Ozand
JournalMetabolism: clinical and experimental (Metabolism) Vol. 47 Issue 8 Pg. 900-2 (Aug 1998) ISSN: 0026-0495 [Print] United States
PMID9711982 (Publication Type: Journal Article)
Topics
  • Adolescent
  • Catheterization, Central Venous (adverse effects, instrumentation)
  • Catheters, Indwelling (adverse effects)
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Metabolic Diseases (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: