Gabapentin relieves trigeminal neuralgia in multiple sclerosis patients.

Abstract

This report describes the effectiveness of gabapentin, a recently approved anticonvulsant, in seven patients with MS experiencing trigeminal neuralgia refractory to treatment with conventional medical therapy. Gabapentin relieved pain completely in six and significantly in the seventh patient. Gabapentin may be a valuable addition to pharmacologic therapy in trigeminal neuralgia, particularly in patients with MS and in refractory cases.

• Authors: O A Khan
• Journal: Neurology (Neurology) Vol. 51 Issue 2 Pg. 611-4 (Aug 1998) ISSN: 0028-3878 [Print] United States
• PMID: 9710050 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Acetates
• Amines
• Analgesics
• Cyclohexanecarboxylic Acids
• gamma-Aminobutyric Acid
• Gabapentin

Topics

• Acetates (therapeutic use)
• Adult
• Amines
• Analgesics (therapeutic use)
• Cyclohexanecarboxylic Acids
• Female
• Gabapentin
• Humans
• Male
• Middle Aged
• Multiple Sclerosis (complications)
• Trigeminal Neuralgia (complications, drug therapy)
• gamma-Aminobutyric Acid