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GSTT1 null genotype frequency in a Turkish population.

Abstract
In humans, glutathione-S-transferases (GSTs) are involved in the detoxification of xenobiotics. A deletion polymorphism in the glutathione S-transferase Theta 1 gene (GSTT1 null genotype) is associated with an increased risk of certain forms of cancer. The distribution of this polymorphism in 240 healthy individuals has been examined, using a polymerase chain reaction (PCR)-based method. The GSTT1 null genotype frequency was 20% in a Turkish Population.
AuthorsB Oke, F Akbas, M Aydin, H Berkkan
JournalArchives of toxicology (Arch Toxicol) Vol. 72 Issue 7 Pg. 454-5 (Jun 1998) ISSN: 0340-5761 [Print] Germany
PMID9708886 (Publication Type: Letter)
Chemical References
  • Glutathione Transferase
Topics
  • Gene Frequency
  • Genotype
  • Glutathione Transferase (genetics)
  • Humans
  • Polymerase Chain Reaction
  • Polymorphism, Genetic
  • Turkey

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