Abstract |
In humans, glutathione-S- transferases ( GSTs) are involved in the detoxification of xenobiotics. A deletion polymorphism in the glutathione S-transferase Theta 1 gene (GSTT1 null genotype) is associated with an increased risk of certain forms of cancer. The distribution of this polymorphism in 240 healthy individuals has been examined, using a polymerase chain reaction (PCR)-based method. The GSTT1 null genotype frequency was 20% in a Turkish Population.
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Authors | B Oke, F Akbas, M Aydin, H Berkkan |
Journal | Archives of toxicology
(Arch Toxicol)
Vol. 72
Issue 7
Pg. 454-5
(Jun 1998)
ISSN: 0340-5761 [Print] Germany |
PMID | 9708886
(Publication Type: Letter)
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Chemical References |
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Topics |
- Gene Frequency
- Genotype
- Glutathione Transferase
(genetics)
- Humans
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Turkey
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