Discordance between FDG uptake and technetium-99m-HMPAO brain perfusion in acute traumatic brain injury.

Abstract

A 28-yr-old woman who sustained a mild traumatic brain injury had an 18F-fluorodeoxyglucose (FDG) PET brain study using coincidence imaging performed on a dual-head gamma camera (MCD version; ADAC, Milpitas, CA) followed 24 hr later by 99mTc-hexamethyl propyleneamine oxime SPECT brain perfusion imaging using a triple-head gamma camera (TRIONIX, Twinsburg, OH). The results of the SPECT brain perfusion study demonstrated decreased frontoparietal cortical brain perfusion, whereas 18F-FDG cerebral uptake was normal. Neuropsychological evaluation suggested frontal lobe involvement. This case demonstrates the possibility of discordance between brain perfusion and glucose uptake in acute mild traumatic brain injury.

• Authors: H H Abu-Judeh, M Singh, J C Masdeu, H M Abdel-Dayem
• Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine (J Nucl Med) Vol. 39 Issue 8 Pg. 1357-9 (Aug 1998) ISSN: 0161-5505 [Print] United States
• PMID: 9708506 (Publication Type: Case Reports, Journal Article)

Chemical References

• Fluorine Radioisotopes
• Radiopharmaceuticals
• Fluorodeoxyglucose F18
• Technetium Tc 99m Exametazime

Topics

• Adult
• Brain (diagnostic imaging)
• Brain Injuries (diagnostic imaging)
• Cerebrovascular Circulation (physiology)
• Female
• Fluorine Radioisotopes
• Fluorodeoxyglucose F18
• Humans
• Radiopharmaceuticals
• Technetium Tc 99m Exametazime
• Time Factors
• Tomography, Emission-Computed
• Tomography, Emission-Computed, Single-Photon