HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Efficacy of topiramate.

Abstract
In controlled clinical trials, topiramate (Topamax) has demonstrated efficacy in refractory patients with complex partial seizures and secondarily generalized tonic-clonic seizures. Approximately 45 percent of 534 patients had a > or = 50 percent reduction in seizure frequency. Limited open label trials have shown that topiramate has broad spectrum activity and may be effective in patients with primary generalized epilepsies. The efficacy of topiramate compares very favourably with the efficacy of other new antiepileptic drugs recently introduced.
AuthorsJ Bruni
JournalThe Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques (Can J Neurol Sci) Vol. 25 Issue 3 Pg. S6-7 (Aug 1998) ISSN: 0317-1671 [Print] England
PMID9706733 (Publication Type: Journal Article, Review)
Chemical References
  • Anticonvulsants
  • Topiramate
  • Fructose
Topics
  • Anticonvulsants (therapeutic use)
  • Epilepsies, Partial (drug therapy)
  • Epilepsy, Generalized (drug therapy)
  • Fructose (analogs & derivatives, therapeutic use)
  • Humans
  • Topiramate

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: