May-Hegglin anomaly: a case of vaginal delivery when both mother and fetus are affected.

Abstract

May-Hegglin anomaly is a rare, autosomal dominant disorder characterized by thrombocytopenia and a variable bleeding tendency. In almost all the case reports in the recent literature, platelet transfusion and cesarean section were performed to avoid maternal and neonatal bleeding. We present a case of a woman with May-Hegglin anomaly who had no history of a bleeding tendency. She had a vaginal delivery and a platelet count of 16,000/mm3; the neonate's platelet count was 35,000/mm3. There were no complications. We advocate a reappraisal of basing platelet transfusion and mode of delivery on the platelet count in patients with May-Hegglin anomaly.

• Authors: A C Urato, J T Repke
• Journal: American journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 179 Issue 1 Pg. 260-1 (Jul 1998) ISSN: 0002-9378 [Print] United States
• PMID: 9704798 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Bleeding Time
• Delivery, Obstetric (methods)
• Female
• Fetal Diseases (genetics, therapy)
• Genes, Dominant
• Humans
• Platelet Count
• Platelet Transfusion
• Pregnancy
• Pregnancy Complications, Hematologic (therapy)
• Thrombocytopenia (genetics, therapy)
• Vagina