[Chemotherapy in the treatment of the early relapse of cervical cancer].

Abstract

OBJECTIVES:

The treatment with chemotherapy in early recidivations or high clinical stages of the carcinoma of the cervix was analysed.

MATERIALS AND METHODS:

17 cases early recidivation or high clinical stages in different histopathological types and clinical stages of the cervix cancer were treated with polychemotherapy (5-FU, Adriamycin, Vincrystin and Cyclophosphamide) and monochemotherapy with Carboplatin. The tolerance of these two chemotherapy programs was assessed.

RESULTS:

The same effectiveness of these two programs was observed, but the side effects after Carboplatin treatment were better tolerated then after polychemotherapy program.

CONCLUSION:

Carboplatin is the drug of choice in the treatment of the early recidivations of the cervix cancer.

• Authors: A Popiela, M Mazurec, A Karmowski
• Journal: Ginekologia polska (Ginekol Pol) Vol. 69 Issue 5 Pg. 226-31 (May 1998) ISSN: 0017-0011 [Print] Poland
• Vernacular Title: Chemioterapia w nawrotowym raku szyjki macicy.
• PMID: 9695317 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adult
• Aged
• Antineoplastic Agents (therapeutic use)
• Carcinoma, Squamous Cell (drug therapy)
• Cystadenocarcinoma, Papillary (drug therapy)
• Female
• Humans
• Middle Aged
• Neoplasm Recurrence, Local
• Neoplasm Staging
• Uterine Neoplasms (drug therapy)