Abstract |
Chickens 14 days old were experimentally inoculated with Mycoplasma gallisepticum (MG) R-P10 strain. After development of respiratory symptoms, birds were left unmedicated or medicated for 5 consecutive days with Difloxacin 5, 7.5 or 10 mg/kg body weight per day or Enrofloxacin at the dose level of 10 mg/kg body weight per day. Evaluation of efficacy was based on body weight, symptoms, post-mortem findings, re-isolation of MG and serology. Results indicated that under the conditions of this experiment, treatment with 7.5 mg Difloxacin per kg body weight for 5 days was already effective against pathogenic MG infection. The dose of 10 mg/kg Difloxacin was equally effective as a dose of 10 mg/kg Enrofloxacin in treating respiratory symptoms.
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Authors | I Kempf, R van den Hoven, F Gesbert, M Guittet |
Journal | Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B
(Zentralbl Veterinarmed B)
Vol. 45
Issue 5
Pg. 305-10
(Jun 1998)
ISSN: 0514-7166 [Print] Germany |
PMID | 9673582
(Publication Type: Journal Article)
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Chemical References |
- Anti-Infective Agents
- Fluoroquinolones
- Quinolones
- Enrofloxacin
- Ciprofloxacin
- difloxacin
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Topics |
- Animals
- Anti-Infective Agents
(therapeutic use)
- Chickens
- Ciprofloxacin
(analogs & derivatives, therapeutic use)
- Enrofloxacin
- Female
- Fluoroquinolones
- Male
- Mycoplasma
(isolation & purification)
- Mycoplasma Infections
(prevention & control, veterinary)
- Poultry Diseases
(prevention & control)
- Quinolones
(therapeutic use)
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