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AChR channel blockade by quinidine sulfate reduces channel open duration in the slow-channel congenital myasthenic syndrome.

AuthorsT Fukudome, K Ohno, J M Brengman, A G Engel
JournalAnnals of the New York Academy of Sciences (Ann N Y Acad Sci) Vol. 841 Pg. 199-202 (May 13 1998) ISSN: 0077-8923 [Print] United States
PMID9668240 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Cholinergic Antagonists
  • Receptors, Cholinergic
  • Recombinant Proteins
  • Quinidine
Topics
  • Cell Line
  • Cholinergic Antagonists (pharmacology)
  • Humans
  • Ion Channel Gating (drug effects, physiology)
  • Myasthenia Gravis (congenital, physiopathology)
  • Point Mutation
  • Quinidine (pharmacology)
  • Receptors, Cholinergic (chemistry, drug effects, physiology)
  • Recombinant Proteins (drug effects, metabolism)
  • Syndrome
  • Transfection

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