[Mushroom poisoning. New possibilities for treatment].

Abstract

Poisonous species of fungi in Germany are very few. Dangerous is the ingestion of raw, spoiled or poisonous mushrooms. There exist no reliable tests to determine whether a mushroom is safe except by expert examination and identification of the mushroom. In clinical practice the classification of mushroom poisoning is possible in muscarine-syndrome, gastroenteritic syndrome and in two-phase-syndrome. 90-95% of lethal mushroom poisonings are due to ingestion of Amanita phalloides. In severe cases extensive hepatic necrosis occurs, characterized by profound abnormalities in liver function caused by hepatic coma. In deep coma mortality rates amount to 70% or more. A new therapeutic measure (coated charcoal hemoperfusion)-first applied in liver failure by Chang (1972) and Williams (1973)-has been performed in 3 patients with severe poisoning after ingestion of Amanita phalloides (each patient had eaten at least 7-10 fungi Amanita phalloides). Two of the patients survived.

• Authors: O Bartels
• Journal: Fortschritte der Medizin (Fortschr Med) Vol. 94 Issue 10 Pg. 539-44 (Apr 08 1976) ISSN: 0015-8178 [Print] Germany
• Vernacular Title: Pilzvergiftungen. Neue Therapiemöglichkeiten
• PMID: 964811 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Amanitins
• Charcoal

Topics

• Adult
• Amanitins (poisoning)
• Charcoal (therapeutic use)
• Female
• Hepatic Encephalopathy (therapy)
• Humans
• Male
• Methods
• Middle Aged
• Mushroom Poisoning (therapy)
• Renal Dialysis