Abstract |
Incorporation of tritiated fucose into the acid-soluble and acid-insoluble fractions of cultured fucosidosis and control fibroblast monolayers was determined over a 10-day period. Fucosidosis cells incorporated significantly more label into the acid-soluble, but not the acid-insoluble fraction, than control cells. The ratio of acid-insoluble radioactivity increased lineraly from 1 to 10 days for the fucosidosis cells, indicating the storage of low molecular weight partial degradation products.
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Authors | S Wood |
Journal | Clinical genetics
(Clin Genet)
Vol. 10
Issue 3
Pg. 183-6
(Sep 1976)
ISSN: 0009-9163 [Print] Denmark |
PMID | 963907
(Publication Type: Journal Article)
|
Chemical References |
- Tritium
- Fucose
- Disaccharidases
- alpha-L-Fucosidase
|
Topics |
- Carbohydrate Metabolism, Inborn Errors
(metabolism)
- Cells, Cultured
- Disaccharidases
(deficiency)
- Fibroblasts
(metabolism)
- Fucose
(metabolism)
- Humans
- Tritium
- alpha-L-Fucosidase
(deficiency)
|