HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Effects of lipemia and trauma on experimental fat embolism.

Abstract
According to some investigators, trauma is thought to bring about physical changes which produce a coalescence of normally dispersed blood lipids into fat droplets and pulmonary fat embolisms. Lipemia is thought to increase the extent of this embolization. If this theory is correct, intravenously infused labeled oil which is retained in the lungs should be mixed with and diluted by the fat emboli originating from the blood. Radioactive olive oil of known specific activity was slowly administered to a) control rats, b) rats made lipemic by dietary measures, c) severely traumatized rats, and d) traumatized lipemic rats. There was no difference in the specific activity of the oil recovered from the lungs of rats of any group, indicating that no recognizable amount of blood lipids had been added to the experimentally produced emboli.
AuthorsF X Hausberger
JournalThe American journal of pathology (Am J Pathol) Vol. 84 Issue 3 Pg. 515-20 (Sep 1976) ISSN: 0002-9440 [Print] United States
PMID961825 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Lipids
  • Oils
Topics
  • Animals
  • Embolism, Fat (etiology)
  • Hyperlipidemias (complications)
  • Lipids (blood)
  • Male
  • Oils (metabolism)
  • Pulmonary Embolism (etiology)
  • Rats
  • Wounds and Injuries (complications)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: