[Therapeutic effect of amigluracil aerosol inhalation on radiation- and bleomycin-induced pulmonitis in patients with malignant lymphomas].

Abstract

The report deals with the first experience of successful administration of soluble amigluracil, a synthesized pyrimidine derivative of methyluracil, which was inhaled with aerosols to treat acute, chronic radiation-related and bleomycin-induced pulmonitis. No side-effects, including allergy, were observed.

• Authors: M L Gershanovich, L V Filatova
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 44 Issue 2 Pg. 221-4 ( 1998) ISSN: 0507-3758 [Print] Russia (Federation)
• Vernacular Title: Lechebnyĭ èffekt aèrozol'nykh ingaliatsiĭ amigluratsila pri luchevom i toksicheskom pul'monite, vyzvannom belomitsinom u bol'nykh zlokachestvennymi limfomami.
• PMID: 9615832 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antibiotics, Antineoplastic
• Bleomycin
• amigluracil
• Uracil

Topics

• Administration, Inhalation
• Adult
• Antibiotics, Antineoplastic (adverse effects)
• Bleomycin (adverse effects)
• Female
• Humans
• Lung Diseases, Interstitial (chemically induced, drug therapy, etiology)
• Lymphoma, Non-Hodgkin (drug therapy, radiotherapy)
• Male
• Middle Aged
• Radiotherapy, Adjuvant (adverse effects)
• Treatment Outcome
• Uracil (administration & dosage, analogs & derivatives, therapeutic use)