Periorbital vasculitis complicating Kawasaki syndrome in an infant.

Abstract

Periorbital vasculitis is a previously unreported complication of Kawasaki syndrome (KS). We describe an infant with severe KS refractory to initial management with salicylate and intravenous immunoglobulin (IVIG). Retreatment with IVIG and high-dose pulsed steroids was required for persistent fever and inflammatory manifestations. Despite aggressive medical therapy, a large left coronary artery aneurysm developed. After apparent complete KS remission, acute periorbital vasculitis developed in the left upper eyelid and orbit, requiring operative intervention for diagnosis and high-dose pulsed steroids for therapy. The significance of this previously unreported ophthalmic complication of KS is reviewed, along with a discussion of the role of steroids in KS manifestations refractory to IVIG.

• Authors: M W Felz, A Patni, S E Brooks, R A Tesser
• Journal: Pediatrics (Pediatrics) Vol. 101 Issue 6 Pg. E9 (Jun 1998) ISSN: 1098-4275 [Electronic] United States
• PMID: 9606251 (Publication Type: Case Reports, Journal Article)

Topics

• Eyelid Diseases (etiology)
• Humans
• Infant
• Male
• Mucocutaneous Lymph Node Syndrome (complications)
• Vasculitis (etiology)