[Between bench and bedside: examples of clinically oriented basic surgery research].

Abstract

Animal experimental studies are an effective modality for testing new therapeutic strategies, provided that the animal model and the study protocol simulate the clinical situation. This is exemplified by various animal experimental studies on the therapy of infectious complications in acute necrotizing pancreatitis that were performed preliminary or supplementary to clinical studies. The results show that basic surgical research with close clinical orientation can be usefully and fruitfully combined with clinical studies and enables the academically active young surgeon to overcome the dualism between laboratory work and clinical practice.

• Authors: H G Hotz, T Foitzik, N Runkel, H J Buhr
• Journal: Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress (Langenbecks Arch Chir Suppl Kongressbd) Vol. 114 Pg. 358-60 ( 1997) ISSN: 0942-2854 [Print] Germany
• Vernacular Title: Between Bench and Bedside: Beispiele klinisch orientierter chirurgischer Grundlagenforschung.
• PMID: 9574154 (Publication Type: English Abstract, Journal Article)

Topics

• Animals
• Disease Models, Animal
• Pancreatitis, Acute Necrotizing (etiology, surgery)
• Risk Factors
• Surgical Wound Infection (etiology, surgery)