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Topical lithium succinate ointment (Efalith) in the treatment of AIDS-related seborrhoeic dermatitis.

Abstract
A randomised, double-blind, placebo-controlled trial with lithium succinate ointment was conducted in patients with AIDS-associated facial seborrhoeic dermatitis. Twice daily applications of the ointment brought about a rapid (2.5 days) and highly significant (P = 0.007) improvement in the severity of the condition. Lithium succinate ointment is well tolerated and can be a useful treatment for seborrhoeic dermatitis in this group of patients.
AuthorsJ A Langtry, C M Rowland Payne, R C Staughton, J C Stewart, D F Horrobin
JournalClinical and experimental dermatology (Clin Exp Dermatol) Vol. 22 Issue 5 Pg. 216-9 (Sep 1997) ISSN: 0307-6938 [Print] England
PMID9536541 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Dermatologic Agents
  • Lithium Compounds
  • Ointments
Topics
  • Acquired Immunodeficiency Syndrome (complications)
  • Dermatitis, Seborrheic (drug therapy, etiology)
  • Dermatologic Agents (therapeutic use)
  • Double-Blind Method
  • Facial Dermatoses (drug therapy, etiology)
  • Humans
  • Lithium Compounds (therapeutic use)
  • Male
  • Ointments
  • Treatment Outcome

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