[Azithromycin in the prevention of Mediterranean spotted fever].

Abstract

Antibodies to Rickettsia conorii were detected by the indirect immunofluorescence (IFA) assay in 64 (51.6%) out of 124 examinees living in North Dalmatia (Croatia) who had a history of recent tick bites during 1994 and 1995. Positive titers of IFA antibodies to R. conorii were detected in 12 (31.5%) out of 38 examinees with carried out prophylaxis by azithromycin. The usual clinical signs of Mediterranean spotted fever were registered in 22 (25.6%) and asymptomatic infection in 30 (34.8%) out of 86 examinees without prophylaxis. Clinical signs of the disease were not registered in examinees with prophylaxis.

• Authors: B Dzelalija, M Morović, T Avsic-Zupanc
• Journal: Lijecnicki vjesnik (Lijec Vjesn) Vol. 119 Issue 10 Pg. 270-2 (Nov 1997) ISSN: 0024-3477 [Print] Croatia
• Vernacular Title: Azitromicin u profilaksi mediteranske pjegave groznice.
• PMID: 9531759 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Azithromycin

Topics

• Adult
• Anti-Bacterial Agents (therapeutic use)
• Azithromycin (therapeutic use)
• Boutonneuse Fever (prevention & control)
• Child
• Humans