An erythema multiforme-like eruption caused by exposure to 1-chloromethylnaphthalene.

Abstract

A young male patient developed an erythema multiforme-like eruption following an accidental exposure to 1-chloromethylnaphthalene (1-CMN). In addition to the skin lesion, he suffered from liver involvement and tear insufficiency. Positive results of a patch test with 1-CMN and an in vitro lymphocyte transformation test suggested that direct exposure of the skin to chemical compounds was the probable cause of his symptoms.

• Authors: S Urano, Y Tokura
• Journal: The Journal of dermatology (J Dermatol) Vol. 25 Issue 1 Pg. 13-8 (Jan 1998) ISSN: 0385-2407 [Print] England
• PMID: 9519603 (Publication Type: Case Reports, Journal Article)

Chemical References

• 1-chloromethylnaphthalene
• Anti-Inflammatory Agents
• Glucocorticoids
• Naphthalenes
• naphthalene
• Methylprednisolone

Topics

• Administration, Topical
• Adult
• Anti-Inflammatory Agents (therapeutic use)
• Chemical Industry
• Chemical and Drug Induced Liver Injury
• Erythema Multiforme (chemically induced, drug therapy)
• Glucocorticoids
• Humans
• Lymphocyte Activation (drug effects)
• Male
• Methylprednisolone (therapeutic use)
• Naphthalenes (adverse effects)
• Occupational Diseases (chemically induced, drug therapy)
• Patch Tests
• Tears (drug effects)
• Xerophthalmia (chemically induced)