Optical monitoring of living brain tissue.

Abstract

Optical methods can usefully augment classical techniques such as electrical recording for investigating cellular and network physiology. Here, recent developments in optical methods--including confocal and nonlinear fluorescence imaging, semiconductor array imaging, and improved fluorescent indicators of ion concentration and transmembrane electrical potential--are briefly reviewed, and examples are offered that may suggest potential applications to experimental studies in alcoholism research.

• Authors: T Hosokawa, M Ohta, A Koyama, K Saito, A Fine
• Journal: Alcoholism, clinical and experimental research (Alcohol Clin Exp Res) Vol. 22 Issue 1 Pg. 60-6 (Feb 1998) ISSN: 0145-6008 [Print] England
• PMID: 9514286 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Ethanol

Topics

• Alcoholism (pathology, physiopathology)
• Animals
• Brain (drug effects, pathology)
• Brain Mapping (instrumentation)
• Culture Techniques
• Ethanol (pharmacology)
• Hippocampus (pathology, physiopathology)
• Image Processing, Computer-Assisted (instrumentation)
• Membrane Potentials (drug effects, physiology)
• Microscopy, Confocal (instrumentation)
• Microscopy, Fluorescence (instrumentation)