7 years experience of photopatch testing with sunscreen allergens in Sweden.

Abstract

Since 1990 7 sunscreen allergens have been included in the standard photopatch protocol at 2 Swedish dermatology clinics. 355 consecutive patients with suspected photosensitivity were tested, and in 28 of these (7.9%), a total of 42 allergic reactions were found. 80% of the reactions were of photocontact origin. The most common allergen was benzophenone-3 (Eusolex 4360), with 15 photocontact and 1 contact allergic reactions, followed by isopropyl dibenzoylmethane (Eusolex 8020) (8 photocontact, 4 contact) and butyl methoxydibenzoylmethane (Parsol 1789), with 6 photocontact reactions. There were 2 cases of photocontact allergy to phenylbenzimidazole sulfonic acid (Eusolex 232), which has not been reported previously. 1 case of contact urticaria from benzophenone-3 was accidentally found. In addition, 21 + reactions of doubtful relevance were noted in 14 patients: 16 on irradiated and 5 on non-irradiated test sites. Among these, irritant and phototoxic reactions may be included. These results indicate that the inclusion of UV filters in the standard photopatch protocol is important. Immediate-type testing for urticaria could also be of value.

• Authors: B Berne, A M Ros
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 38 Issue 2 Pg. 61-4 (Feb 1998) ISSN: 0105-1873 [Print] England
• PMID: 9506215 (Publication Type: Journal Article)

Chemical References

• Allergens
• Sunscreening Agents

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Allergens (administration & dosage, adverse effects)
• Child
• Dermatitis, Allergic Contact (diagnosis, etiology)
• Dermatitis, Photoallergic (diagnosis, etiology)
• Female
• Humans
• Male
• Middle Aged
• Multicenter Studies as Topic
• Patch Tests
• Severity of Illness Index
• Skin (drug effects, pathology, radiation effects)
• Sunscreening Agents (administration & dosage, adverse effects)
• Sweden
• Ultraviolet Rays (adverse effects)
• Urticaria (chemically induced)