Abstract |
Abnormally soluble collagen is synthesized in vitro not only by skin fibroblasts of Marfan patients but also by those of patients with Ehlers-Danlos type V and cutis laxa. The excessive solubility of collagen is corrected by the addition to the culture medium of a synthetic flavonoid, (+)- catechin.
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Authors | G Francis, P V Donnelly, N Di Ferrante |
Journal | Experientia
(Experientia)
Vol. 32
Issue 6
Pg. 691-3
(Jun 15 1976)
ISSN: 0014-4754 [Print] Switzerland |
PMID | 950007
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Benzopyrans
- Collagen
- Hydroxyproline
|
Topics |
- Benzopyrans
(pharmacology)
- Cells, Cultured
- Collagen
(metabolism)
- Cutis Laxa
(metabolism)
- Ehlers-Danlos Syndrome
(metabolism)
- Fibroblasts
(metabolism)
- Humans
- Hydroxyproline
(metabolism)
- Marfan Syndrome
(metabolism)
- Skin
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