Abstract |
Uncontrollable arrhythmia is one of the causes of operative death in CABG. We report two cases of successful treatment of recurrent VT/Vf in CABG operation by MS-551. One case was a 72-year-old male, who had unstable angina and OMI with left ventricular dysfunction (LVEF 24%). After weaning from CPB, the rhythm turned into VT/Vf suddenly. Lidocaine and verapamil were not effective. VT/Vf recurred over the over. The another case was a 52-year-old male, who had OMI and effort angina. He became myocardial infarction during operation. VT/Vf occurred after the weaning from CPB. Lidocaine and amiodarone were of no effect on his VT/Vf. In both cases, intravenous injection of MS-551 promptly stopped VT/Vf. Use of MS-551 was limited mainly on DCM patients. But other antiarrhythmic agents were ineffective on these cases. We have had to continue support circulation for a long time without MS-551. As MS-551 is being used as a trial on medically followed patients, it was unknown how effective clinically on the acute myocardial infarction. In this regard, our cases may suggest a positive answer to that.
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Authors | K Uwabe, M Endo, H Nishida, Y Tomizawa, H Koyanagi, S Ohnishi, H Kasanuki |
Journal | Kyobu geka. The Japanese journal of thoracic surgery
(Kyobu Geka)
Vol. 51
Issue 2
Pg. 108-11
(Feb 1998)
ISSN: 0021-5252 [Print] Japan |
PMID | 9492458
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Anti-Arrhythmia Agents
- Pyrimidinones
- nifekalant
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Topics |
- Aged
- Angina, Unstable
(surgery)
- Anti-Arrhythmia Agents
(therapeutic use)
- Cardiopulmonary Bypass
- Coronary Artery Bypass
- Humans
- Intraoperative Care
- Male
- Middle Aged
- Myocardial Infarction
(surgery)
- Pyrimidinones
(therapeutic use)
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