Oleic and vaccenic acid levels in lipid clases of tumors.

Abstract

The isomeric octadecenoate composition of triglyceride, phosphatidyicholine, and phosphatidylethanolamine classes from a variety of rat and mouse tumors was examined. Phosphatidylethanolamine from the tumors contained a higher percentage of octadecenoate than reported for many normal tissues. The octadecenoate fractions of the three lipid classes from various tumors consisted of ca. 75% or greater oleate, with vaccenate making up the balance. These data indicate that the loss of lipid class specificity for isomeric octadecenoates reported in hepatomas (Lipids 10:746, 1975, and Lipids 9:987, 1974) also occurs in other tumors.

• Authors: R Wood
• Journal: Lipids (Lipids) Vol. 11 Issue 7 Pg. 578-80 (Jul 1976) ISSN: 0024-4201 [Print] United States
• PMID: 948255 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Fatty Acids
• Oleic Acids
• Phospholipids

Topics

• Animals
• Fatty Acids (metabolism)
• Isomerism
• Lipid Metabolism
• Mice
• Neoplasms, Experimental (metabolism)
• Oleic Acids (metabolism)
• Phospholipids (metabolism)
• Rats
• Structure-Activity Relationship