Abstract | AIMS: METHODS: RESULTS: Although intestinal trefoil factor mRNA was expressed consistently in the tumours, the levels of expression varied considerably among the cases examined. The levels of expression were low in advanced stage tumours (Dukes's B, C, and D) compared with early stage tumours (Dukes's A) (p < 0.05). In addition, there was a tendency towards a positive correlation, albeit not well defined, between the amounts of intestinal trefoil factor mRNA and the histological differentiation of tumours. CONCLUSIONS:
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Authors | H Uchino, H Kataoka, H Itoh, M Koono |
Journal | Journal of clinical pathology
(J Clin Pathol)
Vol. 50
Issue 11
Pg. 932-4
(Nov 1997)
ISSN: 0021-9746 [Print] England |
PMID | 9462243
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers, Tumor
- Growth Substances
- Mucins
- Muscle Proteins
- Neuropeptides
- Peptides
- RNA, Messenger
- RNA, Neoplasm
- TFF3 protein, rat
- Trefoil Factor-2
- Trefoil Factor-3
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
(genetics, metabolism)
- Blotting, Northern
- Colorectal Neoplasms
(metabolism, pathology)
- Disease Progression
- Down-Regulation
- Female
- Growth Substances
(genetics, metabolism)
- Humans
- Male
- Middle Aged
- Mucins
- Muscle Proteins
- Neuropeptides
- Peptides
(genetics, metabolism)
- RNA, Messenger
(metabolism)
- RNA, Neoplasm
(metabolism)
- Trefoil Factor-2
- Trefoil Factor-3
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