Abstract | OBJECT: METHODS: Twelve cynomolgus monkeys were randomly divided into two groups and then both groups underwent placement of an arterial autologous blood clot in the subarachnoid space around the right middle cerebral artery (MCA). The five animals in the control group received intravenously administered saline and the seven treated animals received intravenously administered chelator (2,2'-dipyridyl) for 14 days. Sequential arteriography for assessment of MCA diameter was performed before and on the 7th day after SAH. CONCLUSIONS:
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Authors | L L Horky, R M Pluta, R J Boock, E H Oldfield |
Journal | Journal of neurosurgery
(J Neurosurg)
Vol. 88
Issue 2
Pg. 298-303
(Feb 1998)
ISSN: 0022-3085 [Print] United States |
PMID | 9452239
(Publication Type: Journal Article)
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Chemical References |
- Ferrous Compounds
- Iron Chelating Agents
- Transferrin
- 2,2'-Dipyridyl
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Topics |
- 2,2'-Dipyridyl
(adverse effects, therapeutic use)
- Animals
- Cerebral Angiography
- Female
- Ferrous Compounds
(antagonists & inhibitors)
- Injections, Intravenous
- Iron Chelating Agents
(adverse effects, therapeutic use)
- Ischemic Attack, Transient
(diagnostic imaging, prevention & control)
- Liver
(drug effects, pathology)
- Macaca fascicularis
- Male
- Subarachnoid Hemorrhage
(drug therapy)
- Time Factors
- Transferrin
(analysis)
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