Abstract |
The paper summarizes own results of studies on phospholipids and glycolipids from natural biological sources. New approaches for synthesis of inositol-containing sphingophospholipids, glycophosphatidylinositols, semisynthetic synthesis of phosphoglycerols have been introduced. New industrial method of phosphjatidylcholine isolation and production of number of lipid preparations were developed. Incorporation of DOPA into liposomes increases efficacy of its action in the medication of MPTP-induced parkinsonism in mice.
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Authors | V I Shvetz, Iu M Krasnopol'skiĭ, A P Kaplun, A E Stepanov |
Journal | Voprosy meditsinskoi khimii
(Vopr Med Khim)
1997 Sep-Oct
Vol. 43
Issue 5
Pg. 416-24
ISSN: 0042-8809 [Print] Russia (Federation) |
Vernacular Title | Biotekhnologicheskie napravleniia v sozdanii lekarstvennykh i diagnosticheskikh preparatov. |
PMID | 9446330
(Publication Type: English Abstract, Journal Article, Review)
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Chemical References |
- Biological Products
- Diagnostic Uses of Chemicals
- Drug Carriers
- Lipids
- Liposomes
- Pharmaceutical Preparations
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Topics |
- Animals
- Biological Products
(isolation & purification, therapeutic use)
- Biotechnology
(methods)
- Diagnostic Uses of Chemicals
- Drug Carriers
- Drug Therapy
- Humans
- Lipids
(chemical synthesis, isolation & purification)
- Liposomes
- Pharmaceutical Preparations
(administration & dosage, chemical synthesis, isolation & purification)
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