Abstract | OBJECTIVE: METHODS: RESULTS: With the DAT and LOS antigens, a positive result in sera obtained in the 12 months preceding the onset of TB was significantly associated with later development of TB. Using the BDA.TDA antigen, the same association was observed in sera collected during the 6 months before the diagnosis of TB. No significant association was found with the PPD antigen. CONCLUSIONS: These results suggest that specific antibody markers may be useful to evaluate the risk of active TB in HIV-infected individuals, and a helpful indicator for preventive treatment.
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Authors | S Cavalcante, A L Kritski, M A Ferreira, M A Souza, A Laszlo, E B Werneck-Barroso, L S Fonseca |
Journal | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
(Int J Tuberc Lung Dis)
Vol. 1
Issue 2
Pg. 170-4
(Apr 1997)
ISSN: 1027-3719 [Print] France |
PMID | 9441083
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antibodies, Bacterial
- Tuberculin
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Topics |
- AIDS-Related Opportunistic Infections
(blood, immunology)
- Adult
- Antibodies, Bacterial
(analysis)
- Antibody Formation
- Case-Control Studies
- Confidence Intervals
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Male
- Middle Aged
- Mycobacterium tuberculosis
(immunology)
- Odds Ratio
- Sensitivity and Specificity
- Tuberculin
(analysis)
- Tuberculosis
(blood, diagnosis, immunology)
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