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Bioelectrical activity of brain in Rana tigrina (Daudin) in response to phosalone poisoning.

Abstract
An acute dose of phosalone, intraperitoneally injected to Rana tigrina alters the bioelectrical activity of the brain. The frequency levels of delta, theta, alpha, and beta waves remained similar in both control and experimental groups, while the amplitude of the waves was significantly decreased by 40 to 60% in the latter group. The total work done (TWD) was also significantly reduced. The above disturbance in the brain electrical activity may have correlation to the inhibition of cation-linked ATPase, as well as the cholinesterase activity.
AuthorsK Balasandaram, K Ramalingam, V R Selvarajan
JournalComparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology (Comp Biochem Physiol C Pharmacol Toxicol Endocrinol) Vol. 118 Issue 2 Pg. 229-31 (Oct 1997) ISSN: 1367-8280 [Print] United States
PMID9440249 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Cholinesterase Inhibitors
  • Insecticides
  • Organothiophosphorus Compounds
  • phosalone
  • Adenosine Triphosphatases
Topics
  • Adenosine Triphosphatases (antagonists & inhibitors)
  • Animals
  • Brain (drug effects, enzymology, physiology)
  • Cholinesterase Inhibitors (toxicity)
  • Electroencephalography (drug effects)
  • Injections, Intraperitoneal
  • Insecticides (toxicity)
  • Male
  • Organothiophosphorus Compounds (toxicity)
  • Ranidae (physiology)

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