Abstract | PURPOSE: We documented the morphological changes on enhanced MR imaging studies that occur in epidural scar over a period of 1 year after lumbar diskectomy. METHODS: The study population was culled from a randomized, multicenter clinical trial designed to evaluate the efficacy of a device inhibiting postoperative epidural fibrosis after single-level, unilateral laminectomy/ diskectomy for herniated lumbar disk. Analysis was restricted to 71 control subjects who did not receive the device. All patients underwent surgery after receiving clinical and MR examinations, with follow-up MR studies at 6 and 12 months. Evaluation of all MR images was performed by one interpreter, who was blinded to treatment arm and clinical findings. The extent of epidural scar seen at the 6- and 12-month MR examinations was graded on a scale of 0 to 4 for each quadrant at each imaging section encompassing the surgical level. RESULTS: Eighty-five percent of the patients had no change in the amount of anterior epidural scar between the 6- and 12-month MR examinations; 75% of the patients showed no change in the amount of posterior epidural scar between the 6- and 12-month examinations. CONCLUSION: The majority of our patients had no change in the amount of epidural scarring visible at enhanced MR imaging over a 1-year period after lumbar laminectomy/ diskectomy.
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Authors | J S Ross, N Obuchowski, R Zepp |
Journal | AJNR. American journal of neuroradiology
(AJNR Am J Neuroradiol)
Vol. 19
Issue 1
Pg. 183-6
(Jan 1998)
ISSN: 0195-6108 [Print] United States |
PMID | 9432177
(Publication Type: Clinical Trial, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Topics |
- Cicatrix
(pathology, surgery)
- Diskectomy
- Epidural Space
- Fibrosis
(prevention & control)
- Humans
- Intervertebral Disc Displacement
(surgery)
- Laminectomy
- Lumbar Vertebrae
(pathology, surgery)
- Magnetic Resonance Imaging
- Postoperative Complications
(prevention & control)
- Time Factors
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