Abstract |
We investigated the influence of extravariceal collateral channel pattern on the recurrence of esophageal varices after sclerotherapy. One hundred and fifteen patients with cirrhosis and esophageal varices were studied. They were divided into four groups according to extravariceal collateral pattern on portal venography. Group 1 patients had neither paraesophageal veins nor gastrorenal veins (n = 49); group 2 patients had paraesophageal veins only ( n = 30); group 3 patients had gastrorenal veins only (n = 25); and group 4 patients had paraesophageal veins plus gastrorenal veins (n = 11). Sclerotherapy was repeated to eradicate esophageal varices and follow-up endoscopic examination were performed. The overall recurrence-free rate at 36 months was 68%. The log-rank test showed the recurrence-free rate to be significantly higher in group 3 (76%) and group 4 patients (89%) than in group 1 patients (51%; P < 0.05 and P < 0.05, respectively). Although the recurrence-free rate was higher in group 4 than in group 2 patients (59%), this did not reach the level of significance (P = 0.10). No significant differences were found between other pairs of groups. These results suggest that gastrorenal veins play an important role in the protection against recurrent esophageal varices after sclerotherapy, while the protective role of paraesophageal veins appears to be small.
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Authors | T Sakai, T Iwao, K Oho, A Toyonaga, K Tanikawa |
Journal | Journal of gastroenterology
(J Gastroenterol)
Vol. 32
Issue 6
Pg. 715-9
(Dec 1997)
ISSN: 0944-1174 [Print] Japan |
PMID | 9430007
(Publication Type: Journal Article)
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Topics |
- Aged
- Collateral Circulation
- Disease-Free Survival
- Esophageal and Gastric Varices
(complications, pathology, therapy)
- Esophagus
(blood supply)
- Female
- Humans
- Hypertension, Portal
(complications)
- Liver Cirrhosis
(complications)
- Male
- Middle Aged
- Portography
- Recurrence
- Sclerotherapy
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