HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Postoperative miotics for patients with infantile esotropia.

AbstractBACKGROUND AND OBJECTIVES:
To examine the postoperative effect of echothiophate iodide in children who underwent surgery to congenital esotropia, and to find out whether it significantly reduced the residual esotropia.
PATIENTS AND METHODS:
Forty-one children who underwent surgery to correct congenital esotropia were randomly divided into a study group and a control group. The children in the treatment group received echothiophate iodide eyedrops once daily for 4 months, and all the children received dexamethasone eyedrops for 1 week after surgery. The strabismus angle was measured at 6 days, 6 months, and 12 months postoperatively for every patient. The measurements were compared in both groups using the paired Student's t test.
RESULTS:
The surgical procedure reduced the mean angle of esotropia by 32.4 prism diopters (PD) in the treatment group, and 38.8 PD in the control group. Six months after surgery, a mean decrease in the esotropia of 1.0 PD was observed in the treatment group, and a mean increase of 0.2 PD was observed in the control group. Twelve months postoperatively, the esotropia increased, by an average of 1.4 and 2.8 PD in the treatment and control groups, respectively. These differences were not statistically different (P > .05).
CONCLUSION:
Echothiophate iodide, given postoperatively for congenital esotropia, does not improve the surgical results during the first postoperative year.
AuthorsA Spierer, T Zeeli
JournalOphthalmic surgery and lasers (Ophthalmic Surg Lasers) Vol. 28 Issue 12 Pg. 1002-5 (Dec 1997) ISSN: 1082-3069 [Print] United States
PMID9427988 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Glucocorticoids
  • Miotics
  • Ophthalmic Solutions
  • Echothiophate Iodide
Topics
  • Administration, Topical
  • Child
  • Child, Preschool
  • Echothiophate Iodide (administration & dosage, therapeutic use)
  • Esotropia (congenital, drug therapy, surgery)
  • Female
  • Follow-Up Studies
  • Glucocorticoids (administration & dosage, therapeutic use)
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Miotics (administration & dosage, therapeutic use)
  • Ophthalmic Solutions
  • Postoperative Care (methods)
  • Postoperative Period
  • Refraction, Ocular
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: