Abstract | BACKGROUND: Although sun protection is advocated for skin cancer prevention, sunlight is also important in generation of vitamin D in the skin. There is concern that sun protection may result in an abnormally low level of vitamin D. OBJECTIVE: METHODS: We surveyed the patients to determine the extent of sun protection and vitamin D intake and measured the serum levels of two vitamin D metabolites (25-hydroxyvitamin D [25-OHD] and 1,25-dihydroxyvitamin D [1,25-( OH)2D]), calcium, and parathyroid hormone during 6 years. RESULTS: CONCLUSION: Despite rigorous sun protection normal vitamin D levels can be maintained in ambulatory patients with XP.
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Authors | R B Sollitto, K H Kraemer, J J DiGiovanna |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 37
Issue 6
Pg. 942-7
(Dec 1997)
ISSN: 0190-9622 [Print] United States |
PMID | 9418761
(Publication Type: Journal Article)
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Chemical References |
- Dihydroxycholecalciferols
- Keratolytic Agents
- Parathyroid Hormone
- Sunscreening Agents
- Vitamin D
- 1,25-dihydroxyvitamin D
- Isotretinoin
- Calcium
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Topics |
- Administration, Oral
- Adolescent
- Adult
- Ambulatory Care
- Calcium
(blood)
- Chemoprevention
- Dihydroxycholecalciferols
(blood)
- Female
- Follow-Up Studies
- Humans
- Isotretinoin
(administration & dosage, therapeutic use)
- Keratolytic Agents
(administration & dosage, therapeutic use)
- Male
- Middle Aged
- Parathyroid Hormone
(blood)
- Protective Clothing
- Risk Factors
- Seasons
- Skin
(metabolism, radiation effects)
- Sunlight
- Sunscreening Agents
(administration & dosage, therapeutic use)
- Vitamin D
(administration & dosage, analogs & derivatives, biosynthesis, blood, radiation effects)
- Vitamin D Deficiency
(etiology)
- Xeroderma Pigmentosum
(blood, prevention & control)
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