Allergy to phosphorus sesquisulfide: 0.5% pet. is a more appropriate concentration for patch testing.

Abstract

Patch testing was performed with phosphorus sesquisulfide P4S3 in 2 groups containing equal numbers of patients using different concentrations (0.5% P4S3 in pet. and 1% P4S3 in pet., the usual suggested test concentration as recommended by the International Contact Dermatitis Research Group). We found that there was a statistically significant increase in the number of clinically irrelevant irritant reactions in the group tested with the concentration (chi 2 = 16, p < 0.0004). We recommend that patch testing with phosphorous sesquisulfide should be at a reduced concentration of 0.5% pet.

• Authors: A Abdullah, J F Bourke, I S Foulds
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 37 Issue 5 Pg. 210-2 (Nov 1997) ISSN: 0105-1873 [Print] England
• PMID: 9412747 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)

Chemical References

• Allergens
• Phosphorus Compounds
• phosphorus sesquisulfide

Topics

• Allergens (administration & dosage, adverse effects)
• Dermatitis, Allergic Contact (diagnosis, epidemiology, etiology, immunology)
• Dose-Response Relationship, Drug
• Female
• Humans
• Male
• Patch Tests (methods, statistics & numerical data)
• Phosphorus Compounds (administration & dosage, adverse effects)
• Prevalence
• Sensitivity and Specificity
• United Kingdom