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[A trial of the use of rulid, sumamed and makropen in the combined treatment of generalized periodontitis at a stage of exacerbation].

Abstract
In vitro study of the antibacterial activity of macrolide antibiotics azitromycin (sumamed), midicamycin (macropen), roxitromycin (rulide), and erythromycin demonstrated their high activity towards clinical strains of bacteroids, fusobacteria, peptostreptococci, streptococci, and corynebacteria. These antibiotics were effective in the treatment of 62 adult patients with severe and moderate generalized periodontitis. Rulide and sumamed were the most effective, macropen and erythromycin were inferior to them.
AuthorsV N Tsarev, L A Dmitrieva, N A Filatova, A E Romanov, N O Chekhova
JournalStomatologiia (Stomatologiia (Mosk)) Vol. 76 Issue 5 Pg. 4-8 ( 1997) ISSN: 0039-1735 [Print] Russia (Federation)
Vernacular TitleOpyt primeneniia rulida, sumameda i makropena v kompleksnom lechenii generalizovannogo parodontita v stadii obostreniia.
PMID9411932 (Publication Type: Case Reports, Clinical Trial, Comparative Study, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Antifungal Agents
  • Leucomycins
  • Nystatin
  • Roxithromycin
  • Erythromycin
  • Azithromycin
  • midecamycin
Topics
  • Acute Disease
  • Adolescent
  • Adult
  • Anti-Bacterial Agents (therapeutic use)
  • Antifungal Agents (therapeutic use)
  • Azithromycin (therapeutic use)
  • Chronic Disease
  • Drug Therapy, Combination (therapeutic use)
  • Erythromycin (therapeutic use)
  • Humans
  • Leucomycins (therapeutic use)
  • Middle Aged
  • Nystatin (therapeutic use)
  • Periodontitis (drug therapy, microbiology)
  • Roxithromycin (therapeutic use)

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