Primary cardiac lymphoma with infiltration of the atrioventricular node: remission with reversal of the atrioventricular block induced by chemotherapy.

We describe a rare case of primary cardiac lymphoma associated with complete atrioventricular block, with recovery following systemic chemotherapy. A 61 year-old woman was admitted because of a massive pericardial effusion and complete atrioventricular block. Echocardiography disclosed several polypoid masses in the right atrium. A diagnosis of primary cardiac lymphoma was made. After three cycles of chemotherapy, the patient achieved a complete remission, the ECG showed first-degree atrioventricular block, and echocardiography revealed disappearance of the right atrial masses. This is the first report of a patient recovering from primary cardiac lymphoma and complete atrioventricular block following systemic chemotherapy. We conclude that aggressive treatment of this malignancy can improve cardiac function and the patient's prognosis.
AuthorsY Nakayama, S Uchimoto, K Tsumura, H Morii
JournalCardiology (Cardiology) 1997 Nov-Dec Vol. 88 Issue 6 Pg. 613-6 ISSN: 0008-6312 [Print] SWITZERLAND
PMID9397321 (Publication Type: Case Reports, Journal Article)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Atrioventricular Node (drug effects, physiopathology, ultrasonography)
  • Biopsy
  • Echocardiography
  • Electrocardiography
  • Female
  • Follow-Up Studies
  • Heart Block (drug therapy, physiopathology, ultrasonography)
  • Heart Neoplasms (drug therapy, physiopathology, ultrasonography)
  • Humans
  • Immunohistochemistry
  • Lymphoma, T-Cell (drug therapy, physiopathology, ultrasonography)
  • Middle Aged
  • Neoplasm Invasiveness
  • Radionuclide Ventriculography
  • Remission Induction
  • Tomography, X-Ray Computed

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