Abstract | OBJECTIVE: STUDY DESIGN: In this case-control study, cases of placenta previa confirmed at delivery (ascertained by International Classification of Diseases, ninth revision, Clinical Modification, code-based search, N = 40) were compared with a random sample of patients without placenta previa (N = 80) in a ratio of two controls per case. Data on antecedent maternal cocaine use, as well as other potential risk factors for placenta previa, were obtained from a review of the prenatal chart and the hospital record. Categorization of cocaine use was based on either patient self-report or urine toxicologic testing, or both. Multiple logistic regression was performed to assess the association between cocaine and placenta previa while we controlled for other variables. RESULTS: After the effects of other variables were adjusted for, maternal cocaine use was an independent risk factor for placenta previa (adjusted odds ratio = 4.39, 95% confidence interval 1.17 to 16.4). Other significant risk factors included a history of cesarean section and prior elective abortion. CONCLUSION:
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Authors | G A Macones, H M Sehdev, S Parry, M A Morgan, J A Berlin |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 177
Issue 5
Pg. 1097-100
(Nov 1997)
ISSN: 0002-9378 [Print] United States |
PMID | 9396901
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Case-Control Studies
- Cesarean Section
(adverse effects)
- Cocaine
(adverse effects)
- Female
- Humans
- Placenta Previa
(chemically induced)
- Pregnancy
- Risk Factors
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