Abstract | BACKGROUND AND OBJECTIVES: The worldwide increase in antimicrobial resistance in Neisseria gonorrhoeae prompted the authors to evaluate the status and course of resistance in gonococci in Finland. GOALS: STUDY DESIGN: The results were compared with data obtained in three Finnish laboratories in 1986 and contrasted with the development of the incidence of gonorrhea and the prevalence of penicillinase-producing N. gonorrhoeae (PPNG) in Finland, 1976 to 1995. The number of strains with an elevated MIC to ciprofloxacin was assessed by questionnaire. RESULTS: A decrease, from more than 50% in 1986 to 20% in 1993, of strains susceptible to penicillin and tetracycline was observed. The prevalence of PPNG increased from 0% (1976) to 5.7% (1995). In 1995, two strains with a ciprofloxacin MIC of > or = 32 micrograms/ml were reported. No resistance to ceftriaxone or spectinomycin was detected. CONCLUSIONS: In spite of the rarity of gonorrhea and the availability of efficient antimicrobials in Finland, monitoring of the antimicrobial resistance of N. gonorrhoeae remains important.
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Authors | A Nissinen, H Järvinen, O Liimatainen, M Jahkola, P Huovinen |
Journal | Sexually transmitted diseases
(Sex Transm Dis)
Vol. 24
Issue 10
Pg. 576-81
(Nov 1997)
ISSN: 0148-5717 [Print] United States |
PMID | 9383846
(Publication Type: Journal Article)
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Chemical References |
- Cephalosporins
- Ciprofloxacin
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Topics |
- Cephalosporins
(pharmacology)
- Ciprofloxacin
(pharmacology)
- Drug Resistance, Microbial
- Gonorrhea
(drug therapy)
- Humans
- Microbial Sensitivity Tests
- Neisseria gonorrhoeae
(drug effects)
- Time Factors
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