[Successful use of fluconazole against semi-invasive--pulmonary aspergillosis].

Abstract

A 53-year-old man was admitted to the hospital because of productive coughing general malaise, and right-sided chest pain. At 41 years of age he was given a diagnosis of gastric cancer, underwent a and gastrectomy, was treated with anti-cancer drugs. At 49 years of age he suffered from atypical mycobacteriosis and received anti-tuberculosis drugs for 1 year. A chest X-ray film showed infiltrative shadows with a cavity in the right upper lung field. Semi-invasive aspergillosis was diagnosed on the basis of the clinical and radiographic findings, positive sputum cultures, and positive serologic tests. After 8 months of therapy with intravenous and oral fluconazole, no pulmonary aspergillosis was evident. Treatment with fluconazole was effective in this case of semi-invasive aspergillosis.

• Authors: M Mizuguchi, K Nishi, T Amemiya, H Tachibana, T Ohka, H Kurumaya, M Fujimura, T Matsuda
• Journal: Nihon Kyobu Shikkan Gakkai zasshi (Nihon Kyobu Shikkan Gakkai Zasshi) Vol. 35 Issue 6 Pg. 645-9 (Jun 1997) ISSN: 0301-1542 [Print] Japan
• PMID: 9379561 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Fluconazole

Topics

• Antifungal Agents (therapeutic use)
• Aspergillosis (drug therapy, pathology)
• Aspergillus fumigatus
• Fluconazole (therapeutic use)
• Humans
• Lung Diseases, Fungal (drug therapy, pathology)
• Male
• Middle Aged