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[Posterior scleritis in Wegener disease].

AbstractBACKGROUND:
Wegener's granulomatosis is a focal necrotizing granulomatous vasculitis of unknown etiology. It manifests initially as localized inflammation, usually of the lungs, and preceeds to the state of generalisation which can be life-threatening due to renal failure. Ocular and orbital involvement occurs in 28-58% of patients with Wegener's granulomatosis. More often, the anterior segments of the eye are involved whereas inflammation of the posterior segments is quite uncommon.
PATIENTS AND METHODS:
We report a case of posterior scleritis as the initial manifestation of Wegener's granulomatosis in a 65-year-old woman.
RESULTS:
Posterior scleritis responded favourably to therapy with systemic steroids and cyclophosphamide.
CONCLUSIONS:
Wegener's granulomatosis can have a poor prognosis if not diagnosed and treated in time. Knowledge of posterior scleritis as a possible presenting symptom may therefore facilitate early diagnosis and treatment and prevent progression of the disease.
AuthorsA B Arnavaz, K Freissler, G E Lang
JournalDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft (Ophthalmologe) Vol. 94 Issue 8 Pg. 595-9 (Aug 1997) ISSN: 0941-293X [Print] Germany
Vernacular TitleSkleritis posterior bei Morbus Wegener.
PMID9376701 (Publication Type: Case Reports, English Abstract, Journal Article)
Topics
  • Aged
  • Female
  • Fluorescein Angiography
  • Granulomatosis with Polyangiitis (diagnosis)
  • Humans
  • Retinal Detachment (diagnosis)
  • Sclera (pathology)
  • Scleritis (diagnosis)

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