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DHFR gene point mutation as a predictor of Plasmodium falciparum resistance to cycloguanil in malaria cases from Africa imported to France.

AuthorsR Durand, O Ramiliarisoa, Y Sécardin, P Eldin de Pécoulas, L K Basco, J Le Bras
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene (Trans R Soc Trop Med Hyg) 1997 Jul-Aug Vol. 91 Issue 4 Pg. 460-1 ISSN: 0035-9203 [Print] England
PMID9373655 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antimalarials
  • Triazines
  • cycloguanil
  • Serine
  • Asparagine
  • Tetrahydrofolate Dehydrogenase
  • Proguanil
Topics
  • Animals
  • Antimalarials (therapeutic use)
  • Asparagine
  • Drug Resistance (genetics)
  • Humans
  • Malaria, Falciparum (drug therapy)
  • Plasmodium falciparum (drug effects, genetics)
  • Point Mutation
  • Polymerase Chain Reaction
  • Proguanil
  • Serine
  • Tetrahydrofolate Dehydrogenase (genetics)
  • Travel
  • Triazines (therapeutic use)

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