Pseudohypoaldosteronism with pyloric stenosis--a patient report.

Abstract

A 53 day-old infant was referred for failure to thrive and persistent vomiting with severe dehydration. He had hyponatremia and hyperkalemia. Pyloric stenosis was diagnosed by means of sonography. Poor weight gain, hyponatremia and hyperkalemia were still found after Fredet-Ramsted pyloromyotomy. A urinary tract infection, a high urinary Na+/K+ ratio, and high serum levels of aldosterone and renin were found at the second admission. Rehydration, hydrocortisone and florinef administration failed to correct hyponatremia and hyperkalemia, suggesting pseudohypoaldosteronism. This patient gained weight after treatment of his infection and salt replacement.

• Authors: Y M Wang
• Journal: Journal of pediatric endocrinology & metabolism : JPEM (J Pediatr Endocrinol Metab) 1997 Jul-Aug Vol. 10 Issue 4 Pg. 429-31 ISSN: 0334-018X [Print] Germany
• PMID: 9364371 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Sodium Chloride
• Aldosterone
• Sodium
• Renin
• Potassium

Topics

• Aldosterone (blood)
• Anti-Bacterial Agents (therapeutic use)
• Humans
• Hyperkalemia (etiology)
• Hyponatremia (etiology)
• Infant
• Male
• Potassium (urine)
• Pseudohypoaldosteronism (complications, drug therapy)
• Pyloric Stenosis (complications, diagnostic imaging, surgery)
• Renin (blood)
• Sodium (urine)
• Sodium Chloride (therapeutic use)
• Ultrasonography
• Urinary Tract Infections (complications, drug therapy)