Oral rehydration with a plantain flour-based solution in children dehydrated by acute diarrhea: a clinical trial.

Abstract

A clinical trial was conducted in order to prove the efficacy of a solution containing 50 g/l of plantain flour and 3.5 g/l of sodium chloride (NaCl) for the rehydration of children with acute diarrheal diseases. 121 children were given WHO-ORS (Group A) and 117 a plantain flour-based solution (Group B). Rehydration was successful in 85.9% in Group A and 88.0% in Group B (p = 0.634). Rehydration was completed in 5.28 h (SD 1.99) in Group A and in 4.88 h (SD 2.11) in Group B (p = 0.132). The average solution intake for rehydration was 24.56 ml/kg/h (SD 10.12) in Group A and 21.17 ml/kg/h (SD 9.35) in Group B (p = 0.00782). The mean stool output during rehydration was 8.45 g/kg/h (SD 9.72) in Group A and 4.69 g/kg/h (SD 4.98) in Group B (p = 0.00053). Decrease in blood levels of sodium and potassium occurred in some children in group B. The plantain flour-based solution proved effective for the treatment of dehydration due to acute diarrheal diseases and should be considered as an alternative when standard WHO-ORS is not available.

• Authors: M M Arias, G M Alcaráz, C Bernal, G González
• Journal: Acta paediatrica (Oslo, Norway : 1992) (Acta Paediatr) Vol. 86 Issue 10 Pg. 1047-51 (Oct 1997) ISSN: 0803-5253 [Print] Norway
• PMID: 9350881 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Rehydration Solutions

Topics

• Diarrhea, Infantile (therapy)
• Female
• Flour
• Fluid Therapy (methods)
• Humans
• Infant
• Male
• Rehydration Solutions
• Treatment Outcome
• Zingiberales