[Hormone inactive neuroendocrine tumors of the pancreas].

Abstract

During the past 10 years (1987-1996), 842 laparotomies were performed for pancreatic or periampullary neoplasms; in 25 patients (2.9%) a neuroendocrine tumor was diagnosed. In 19 of these 25 patients (76%) a non-functioning endocrine tumor and in 6 patients (24%) a hormone-active tumor (four insulinoma, one gastrinoma, one VIPoma) was found. Of 19 non-functioning neuroendocrine tumors, 14 were malignant. The resection rate of these malignant tumors was 78.6% (11 of 14; 3 resections were palliative); in comparison, the resection rate of ductal pancreatic carcinoma in our hospital was 28.1%. The probability of 5-year survival amounts to 73% after surgical resection in malignant endocrine tumors and to 19% in ductal pancreatic carcinoma (including palliative resections). As it is not always clear whether non-functioning endocrine tumors are benign or malignant, oncological resection is recommended. Adjuvant chemotherapy seems not to be necessary.

• Authors: M Schwab, M R Knoll, D Jentschura, E Hagmüller
• Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen (Chirurg) Vol. 68 Issue 7 Pg. 705-9 (Jul 1997) ISSN: 0009-4722 [Print] Germany
• Vernacular Title: Hormoninaktive neuroendokrine Tumoren des Pankreas.
• PMID: 9340236 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Aged
• Ampulla of Vater (pathology, surgery)
• Carcinoma, Ductal, Breast (diagnosis, pathology, surgery)
• Common Bile Duct Neoplasms (diagnosis, mortality, pathology, surgery)
• Female
• Gastrinoma (diagnosis, mortality, pathology, surgery)
• Humans
• Insulinoma (diagnosis, mortality, pathology, surgery)
• Male
• Middle Aged
• Neoplasm Staging
• Neuroendocrine Tumors (diagnosis, mortality, pathology, surgery)
• Palliative Care
• Pancreas (pathology)
• Pancreatectomy
• Pancreatic Neoplasms (diagnosis, mortality, pathology, surgery)
• Prognosis
• Survival Rate
• Vipoma (diagnosis, mortality, pathology, surgery)